Levamisole - Prohibit

[TOPalmer3rd]

Hello all. New here but been around goats for a little over a year. I have a small herd of 15 in central florida. They are a boer/kiko mix. I have wormed in the past with ivermectin and cydectin orally. It has been almost 3 month since the last dworming. Almost the entire herd is starting to dry cough. I have not had any fecal tests done to date. I have been solely worming per eyelid color. My herds mucous membranes are not real pink but not white either. I have two does that just kidded. They are coughing worse than any of the rest of them. One of them can't even run without going into a coughing fit. I may have let it go to long. I was afraid to give her something because she was so far into her pregnancy that I didn't want to jeprodize any of her offspriong or her. After doing some research I am seeing mixed opinions on Levamisole - porohibit. In this area people are having an issue with resistance with Ivermectin.

I purchased the small pouch of prohibit from jeffers last week and recieved it in mail yesterday. I read to dose it 12mg per 1 kg of body weight on this forum. Sorry but I don't understand how to figure that one out. I have split the package into 4 equal parts. Each is to get exactly one cup of water added to it. I can accurately measure the weight of the goat with a scale and I can acurately measure in cc's or ml's but not mg's.


So with that said. Opinions using this stuff. How do I dose it. Any negatives anyone has experienced with this??

Thanks
Tom

 

[Roll farms]

FWIW, I do a lot of reading about worms / dewormers and it's my understanding that it's not just resistance that's the problem, more that the wrong dewormers are used at the wrong dosages.

I've also read that deworming w/ ivomec orally won't help w/ lungworm (if that's what you're suspecting) and that you can inject it a the cattle dose to treat lungworm. I would repeat in 21 days.

I've always used Valbazen for lungworm treatment (not safe for bred does, though) and had good luck.

I've never used levamisole.
I bought some....read how dangerous it is if overdosed, and I had the same problem you did trying to figure out the dosage, and so I gave up and took it back.

I use ivermectin at 1cc per 25# for stomach worm, Valbazen for lung worm / liver flukes and sometimes for stomach worms at 1cc per 40#, safeguard for tape worms at 3x the label dose for 3 days straight.

I use Cydectin *only* as a last resort...I've had a 100 ml bottle for 2 years and it's barely been used.

 

[mogolady]

I have never used the this wormer but I have a friend that has with no problems. I know you just have to be very accurate with weights.

Too figure the amount it should tell you the strength after reconstitution. Like, ?mg/?ml.

Then take the weight of your goat in pounds, divide it by 2.2 which is the conversion from pounds to kilograms.

Then you would take the 12mg x ?ml. Take that answer and divide by the ?mg. That will tell you how many mls it take to get 12 mg. of the Levamisole.

Example: IF??? reconstitued it is 10mg/1ml. Then 12mg x 1 ml /10mg = the number of mls needed to get 12 mg.

BUT, you said it says 12mg per kg. Then, you would multiply that by the kg you got by divide pounds/kg. Like I said, I have never used this wormer but that sounds like an awful lot to dose. When you look at the Jeffers site for sheep (and I know goats metabolize differently) it is only 1ml for every 50 pounds. So I would double check dose.

Hope this helps!

 

[TOPalmer3rd]

Thanks for the replies thus far. The recommended dosages for sheep seem to be an acceptable amount in my opinion. I did the math on the 12mg/kg and that just seems like way to much to be given orally. I am not sure where this figure came about but I would like a second opinion on dosing.

I have a 160 lb herd sire named Cody. If I were to dose him the 12mg/kg method this is the math I came up with.

160lbs = 72.7 kg

12mg X 72.7 = 872.7 mg


If that amount is correct then how many mgs per ml in the standard mixture of a 46.8 gram package mixed with one quart of water???

I actually called Agrilabs and they would not give any advice since I was administering it to goats.

ANy help would be appreciated.

I can very clearly see how one can miscalculate a dosage.



THx
Tom

 

[Roll farms]

Call 'em back and "pretend" you're giving it to sheep???

 

[mogolady]

I'm glad your checking it out. I wouldn't want you to OD them.

There is another forum I visit that has always been very good on info and they say:' "give 2 Tablets/100 lbs (3.5mg/lb) or 1 oz/100lbs--5mg/lb.

But again I have never used it. I know with other wormers like the Cydectin Sheep Drench you double because of goats metabolize differently, but like you said, when you do the math, that is waaaaaaay over double. I agree until you know for sure, I would think sheep dose would be safest. I do know you aren't supposed to give it to pregant does. Just FYI if you didn't already know.


Good luck!

 

[TOPalmer3rd]

I read somewhere but can't seem to find out where that it is 900mg/ml but I want to double check. Still searching

Tom

 

[cmjust0]

If that amount is correct then how many mgs per ml in the standard mixture of a 46.8 gram package mixed with one quart of water???

There are 46,800mg of levamisole in a 46.8g package, and there are 946ml in a quart.

That's about 49.5mg of levasole per ml of solution.

I have a 160 lb herd sire named Cody. If I were to dose him the 12mg/kg method this is the math I came up with.

160lbs = 72.7 kg

12mg X 72.7 = 872.7 mg

So if you divide 872.7 by 49.5, you get 17.63ml. That might sound like a lot of liquid, but it's really just a teensy bit more than half a nyquil cap full...a little bit more than a tablespoon.

Bear in mind that I'm not making any guarantees here, so double, triple, quadruple check that math, and understand that if you get the same numbers I get and dose him based on that, it's still on you if he keels over dead..

I'm just here to *try* and help with the math.

( )

 

[Roll farms]

I was hoping he'd come along...

I just do NOT have a head for 'figures'...

 

[cmjust0]

Actually, the easiest solution to this problem would *probably* be to simply mix is according to label directions and then dose at 1.5x whatever the package says for sheep.. I don't *know* that to be true, but I'm pretty sure sheep get 8mg/kg, whereas goats get 12mg/kg.

On the downside...you'd also be wasting the lion's share of a packet of Prohibit unnecessarily on 12 goats, because most would go unused and would eventually have to be discarded.. :/